- Updates regarding the assessment and treatment of ovulatory disorders
- Ovulation induction with letrozole in anovulatory patients
- Advances in in vitro fertilization, including genetic screening
- Fertility preservation options, including in vitro oocyte maturation, ovarian tissue cryopreservation, and mature oocyte cryopreservation
Latest Updates
The Use of Adjuvant or Neoadjuvant Chemotherapy in Extremity and Truncal Sarcoma
- Soft tissue sarcomas are heterogeneous tumors with diverse behavior and response to therapy.
- Increasing data favor a histology-driven approach to soft tissue sarcoma multidisciplinary treatment.
- Chemotherapy in the management of primary resectable soft tissue sarcoma is controversial and evolving.
- Recent evidence supports a more routine use of neoadjuvant chemotherapy in high-risk soft tissue sarcoma.
- Recent suggest that narrow, but negative margins with radiotherapy lead to favorable local control rates.
Squamous Cell Carcinoma of the Esophagus
- Endoscopic therapy has become a definitive therapeutic modality for intramucosal disease.
- Definitive chemoradiation has become an alternative strategy in patients demonstrating a complete clinical response
- Trimodality therapy has emerged as a preferred approach in most operable patients with resectable tumors.
Squamous Cell Carcinoma of the Esophagus
- Endoscopic therapy has become a definitive therapeutic modality for intramucosal disease.
- Definitive chemoradiation has become an alternative strategy in patients demonstrating a complete clinical response
- Trimodality therapy has emerged as a preferred approach in most operable patients with resectable tumors.
Antepartum and Postpartum Hemorrhage
- Delineation of obstetric hemorrhage class based on blood loss in addition to vital sign changes
- Use of Maternal Early Warning Criteria for early detection of acute hemorrhage
- Use of obstetric hemorrhage emergency flowcharts to help guide resuscitation
- Use of rotational thromboelastometry to guide obstetric hemorrhage blood product administration
- Early use of tranexamic acid to reduce obstetric hemorrhage mortality
The Use of Adjuvant or Neoadjuvant Chemotherapy in Extremity and Truncal Sarcoma
- Soft tissue sarcomas are heterogeneous tumors with diverse behavior and response to therapy.
- Increasing data favor a histology-driven approach to soft tissue sarcoma multidisciplinary treatment.
- Chemotherapy in the management of primary resectable soft tissue sarcoma is controversial and evolving.
- Recent evidence supports a more routine use of neoadjuvant chemotherapy in high-risk soft tissue sarcoma.
- Recent suggest that narrow, but negative margins with radiotherapy lead to favorable local control rates.
Benign and Malignant Thyroid Diseases
- The Bethesda classification system is widely used to report the cytologic appearance of thyroid nodule aspirate.
- Molecular marker and gene tests have been developed to assist in predicting the malignancy of thyroid nodules.
- A completely encapsulated follicular variant of papillary thyroid cancer has recently been reclassified as NIFTP.
- Vascular neurosurgery and neurology have dramatically evolved from the 1980s to currently allow for treatment of complex intracranial revascularization, aneurysm, and vascular malformations using intraoperative angiography.
- Endovascular advances with microcatheter, coils, balloon systems, liquid embolic materials, and stent technology will improve revascularization and successful aneurysm exclusion rates while reducing rebleeding and long-term recurrences.
- Current clinical trials are attempting to achieve maximal intracerebral hemorrhage evacuation with nondisruptive surgical access modalities. For instance, the ENRICH trial seeks to compare outcomes between standard medical management to early ( < 24 hours) surgical hematoma evacuation using minimally invasive parafascicular surgery. The estimated study completion date is July 2020.
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