Latest Updates

Solitary Fibrous Tumors

Shefali Chopra, MD, James S Hu, MD, Gino K In, MD, Lawrence R Menendez, MD, Dakshesh Patel, MD, Omar Ragab, MD, Stephen F Sener, MD, William W Tseng, MD
    • Identification of the NAB2-STAT6 fusion as a key genetic aberration in SFTs
    • Recognition of subsets of SFTs with more aggressive clinical behavior
    • Development of a simple risk assessment model

Solitary Fibrous Tumors

Shefali Chopra, MD, James S Hu, MD, Gino K In, MD, Lawrence R Menendez, MD, Dakshesh Patel, MD, Omar Ragab, MD, Stephen F Sener, MD, William W Tseng, MD
    • Identification of the NAB2-STAT6 fusion as a key genetic aberration in SFTs
    • Recognition of subsets of SFTs with more aggressive clinical behavior
    • Development of a simple risk assessment model

Infertility Treatment: Ovulation Induction and Insemination

Alan H. DeCherney, MD, Quinton Katler, MD, Jessica R Zolton, DO
    • PCOS Letrozole is considered as the first-line treatment for ovulation induction for patients with PCOS.
    • Luteal support: Luteal progesterone support is beneficial to patients undergoing gonadotropin stimulation and intrauterine insemination
    • Unexplained Infertility: Gonadotropin treatment is associated with a significantly elevated risk of multiple gestations gestations

Nutrition and Fetal Origins of Diseases in Adults

Amanda K Barks, Michael K Georgieff, MD, Anne Maliszewski-Hall, MD, Phu V Tran, PhD

    Nutrition for the Healthy Adult

    Marijane G. Staniec, MS, RD/LDN, CNSC
      • Latest recommendations for added sugar
      • New guidelines about dietary cholesterol—a license to consume as much as we want?
      • The latest about processed meat; is any amount safe?
      • Shift from single nutrients to whole foods and patterns of eating
      • Using anthropometrics in the primary care setting to determine adiposity

    Management of Non–Muscle-Invasive Bladder Cancer

    Peter C Black , MD
      • Molecular characterization of NMIBC by RNA sequencing has revealed molecular subtypes similar to muscle-invasive bladder cancer.
      • Fluorescent cystoscopy in combination with white light cystoscopy at the time of transurethral bladder tumor resection reduces the risk of subsequent bladder tumor recurrence.
      • Maintenance intravesical BCG therapy can be discontinued after 12 months in patients with intermediate-risk NMIBC but should be continued for 36 months in patients with high-risk NMIBC.
      • The refinement of the definition of the “BCG refractory” and its replacement with the term “BCG unresponsive” by an FDA-AUA panel has contributed to active drug development and clinical trials in this disease state. 

    Energy Balance, Exercise, and Cancer Risk

    Elaine B Trujillo, MS, RD
      • Obesity is the leading modifiable cause of cancer in the United States.
      • Body Mass Index (BMI) as a measurer of body fatness has limitations in the cancer population.
      • Dual-energy x-ray absorptiometry, bioelectrical impedance analysis, computed tomography, and magnetic resonance imaging may be used more frequently in cancer patients.
      • Cancer patients with elevated BMIs have improved survival compared with normal-weight patients.

    Seronegative Spondyloarthritis: Epidemiology, Pathogenesis, And Pathology

    Walter P Maksymowych, MB, ChB, FRCP (UK), FRCPC, FACP
      • Disease association with the IL23R gene and the key role of IL-23 in the activation and expansion of a distinct phenotype of T helper (Th) cell characterized by expression of IL-17, the Th17 cell, represents a major advance in our understanding of spondyloarthritis.
      • Increasing evidence supports a role for innate lymphoid cells (ICLs) in the pathogenesis of spondyloarthritis, especially group 3 ILCs that produce IL‑17 and IL‑22.
      • New genetic associations have been described with three new aminopeptidases (ERAP2, LNPEPP, and NPEPPS), protective variants having reduced rates of peptide cleavage, thereby changing both the length and amino acid composition of peptides available for binding to B27.  
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