Latest Updates

Diagnostic and Therapeutic Principles In Allergy

Mitchell H. Grayson, MD, Peter Mustillo, MD
    • Development of biologic therapies (primarily anti-cytokine) for the treatment of allergic diseases including asthma.
    • Use of sIgE component testing for diagnosis and treatment of food allergy
    • Early peanut introduction to prevent peanut allergy
    • Novel treatment options for food allergy

Dermatologic Wounds

Luis J Borda, MD, Jose A Jaller, MD, Penelope J Kallis, BS, Robert S Kirsner, MD, PhD
    • Compression should be considered in patients with leg ulcers and  ankle brachial index greater  than 0.8.
    • Pyoderma gangrenosum lesions ≤2 cm2 may benefit from topical/intralesional corticosteroids
    • Chronic hydroxyurea therapy may lead to leg ulcers. Lesions typically occur near the malleolar area.
    • Proper diagnosis/therapy of the underlying condition are key when clinicians are face atypical wounds.  

Medical Management of Transplant Patients

Nelson B Goes, MD, Nidyanandh Vadivel, MB, BCh
    • Alternatives therapies calcineurin inhibitors to prevent kidney allograft fibrosis.
    • Maintenance immunosuppression with belatacept preserves glomerular filtration and increases kidney allograft survival.
    • Better understanding and management of post transplant diabetes mellitus.

Upper Blepharoplasty

Tiffany N Ballard, MD, Robert H Gilman, MD, DMD
    • The crush and snip technique is a quick and relatively bloodless method for skin removal in blepharoplasty.
    • Care should be taken not to overresect fat and leave a sunken appearance to the upper eyelid.
    • A simple Q-stick swab is one of the most useful instruments for the procedure of blepharoplasty.

Postresuscitation Management And Outcomes

Shamai A. Grossman, MD, MS, Patrick Hughes, MD, Oren Mechanic, MD, MPH
    • Therapeutic hypothermia is recommended for comatose survivors of cardiac arrest. The most recent evidence suggests that avoiding pyrexia may be the most important factor.
    • The AHA recommends against prehospital cooling with cold intravenous fluid.
    • Percutaneous coronary intervention is an independent predictor of survival.
    • Prognostication is not recommended until 72 hours after return to normothermia in patients undergoing therapeutic hypothermia.
    • Debriefing has been shown to improve several metrics of subsequent resuscitations.

Evaluation Of Elevated Transaminases In Children

Udeme D Ekong, MD, MPH, Pamela L Valentino, MD, MSc, FRCPC
    • The threshold for the upper limit of normal for ALT is lower in children than previously reported based on studies of healthy, nonobese children.
    • NAFLD needs to be identified and addressed in childhood as obese adolescents have a higher rate of complications in adulthood.
    • NAFLD is a common indication for liver transplantation in adults.

Viral Hepatitis C: Treatment

Raymond T. Chung, MD, Jacinta A Holmes, MBBS, PhD, Anna Lidofsky, BS, Jay Luther, MD, Stephanie M Rutledge, MBBCh BAO MRCPI
    • Recent advances in treatment of chronic HCV to include interferon-free direct-acting antiviral agent regimens
    • Latest treatment recommendations, including special populations
    • Issues surrounding treatment-emergent resistance-associated variants 

Minimally Invasive Approaches to Forehead Rejuvenation

Paul S Cederna, MD, Dhivya R Srinivasa, MD
    • Evolution in fixation techniques
    • Endoscopic dissection
    • Temporal changes in the Aesthetic Brow
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