- Development of effective immunotherapies hinges on addressing the immunosuppressive tumor microenvironment to overcome immune tolerance.
- Immunotherapies aimed at reengaging the antitumor immune response have yielded encouraging preclinical and clinical results.
- Alternatively, neutralizing immunotherapies target inhibitory immune mechanisms within the cancer setting, resulting in impressive clinical responses.
- Novel combinatorial immunotherapy approaches hold great promise for establishing durable clinical responses.
Latest Updates




- Oral antibiotics for dental pain are indicated if concomitant fever, purulence, intraoral swelling, extraoral swelling, and trismus.
- Penicillin is first line, with alternatives amoxicillin, amoxicillin-clavulanate, azithromycin, and clindamycin.
- Dysphagia is a red flag symptom in patients with odontogenic abscess, possibly indicating deep space infection.
- Gingivitis is a common condition reversible by oral hygiene, and also associated with cardiovascular disease and other systemic illnesses.
- Malocclusion, unilateral swelling, trismus, jaw deviation, and bony point tenderness or step–off, and positive tongue blade test should prompt the provider to obtain a maxillofacial CT scan for mandible fracture.


- Complete listing of indications for performing VCUG
- Review of radiation exposure experienced during VCUG study in comparison with other imaging modalities
- Description of proper protocol to be performed for management of patients undergoing VCUG
- Discussion of alternative techniques to VUR investigation, including cyclic VCUG, PIC cystography, and nuclear medicine VCUG
- Thorough pictorial overview of the many different types of pathology that can be identified on VCUG


Malignant Diseases of the Peritoneum and Retroperitoneum
- Hyperthermic intra-abdominal chemotherapy treatment in the setting of colorectal carcinomatosis, gastric carcinomatosis, pseudomyxoma peritonei
- Enhanced understanding of the pathophysiology of pseudomyxoma peritonei


Malignant Tumors of the Spleen
- Role of imaging for preoperative characterization of splenic lesions
- Use of laparoscopy for splenectomy


Adjuvant Radiation for Tissue Extremity and Truncal Sarcomas
- Indications for radiation therapy
- Sequencing of radiation therapy
- Technique for radiation delivery