- The currently FDA-approved antipsychotics can be divided into two classes: typical antipsychotics and atypical antipsychotics.
- Antipsychotics are used to treat a variety of psychiatric disorders.
- Typical antipsychotics are effective for the treatment of positive symptoms, whereas atypical antipsychotics also have an effect on the negative symptoms of schizophrenia.
- The typical antipsychotics are generally associated more with the side effects of the extrapyramidal movement, whereas the atypical antipsychotics have a higher risk for metabolic adverse effects.
- Decreasing adverse effects and improving adherence are the goals of treatment with antipsychotic medications.
Latest Updates




- Compartment syndrome of the extremity is a clinical diagnosis in an awake and alert patient.
- Measurement of intracompartmental pressures should be performed in the obtunded patient or if clinical assessment is inconclusive.
- Once the diagnosis is made, emergent fasciotomy is the treatment of choice as time to fasciotomy is the most important factor determining outcome.
- Any patient with risk factors for developing abdominal hypertension should have intra-abdominal pressure assessed, preferably via intermittent or continuous transbladder pressure.
- Patients diagnosed with abdominal compartment syndrome require emergent decompressive laparotomy and the creation of a temporary abdominal closure.


- Tranexamic acid may help with bleeding in rhinoplasty and has been used in craniofacial literature to stop bleeding.
- Preoperative discussion and evaluation is crucial when discussing and planning rhinoplasty for patient satisfaction.
- Free tissue transfer can be utilized if the latter methods have failed in a persistent septal perforation.


Evaluation and Management of Facial Burns
- Synthetic biodegradable dermal matrices are a recent innovation which regenerates a neodermis, with implications for wound coverage in burns and may confer benefits including decreased risk of infection and lower cost.
- 3-D printing of skin is a new frontier in tissue engineering, involving suspension and growth of keratinocytes and fibroblasts in a collagen matrix, with promising results in early animal studies.
- Although face transplantation has been previously performed for debilitating burns of the head and neck, the number of face transplants has declined; reasons for this are multifactorial.


Congenital Malformations of the Ear
- There remains controversy on the true origin and developmental stages of the external ear
- Auricular reconstruction for microtia is complex and constantly evolving
- Classification of auricular anomalies should focus on describing the anatomic subunits involved


Operative Exposure of Abdominal Injuries and Closure of the Abdomen
- Prehospital control of bleeding with tourniquets, and permissive hypotension until operative bleeding control improve survival.
- Damage control resuscitation and surgical principles improve outcomes in patients with abdominal trauma, impaired physiology.
- Resuscitative Endovascular Balloon Occlusion of the Aorta, may aid the hemorrhaging abdominal trauma patient.


Operative Exposure of Abdominal Injuries and Closure of the Abdomen
- Prehospital control of bleeding with tourniquets, and permissive hypotension until operative bleeding control improve survival.
- Damage control resuscitation and surgical principles improve outcomes in patients with abdominal trauma, impaired physiology.
- Resuscitative Endovascular Balloon Occlusion of the Aorta, may aid the hemorrhaging abdominal trauma patient.


- Compartment syndrome of the extremity is a clinical diagnosis in an awake and alert patient.
- Measurement of intracompartmental pressures should be performed in the obtunded patient or if clinical assessment is inconclusive.
- Once the diagnosis is made, emergent fasciotomy is the treatment of choice as time to fasciotomy is the most important factor determining outcome.
- Any patient with risk factors for developing abdominal hypertension should have intra-abdominal pressure assessed, preferably via intermittent or continuous transbladder pressure.
- Patients diagnosed with abdominal compartment syndrome require emergent decompressive laparotomy and the creation of a temporary abdominal closure.