Latest Updates

Systemic Antifungal Agents

    • Evidence for efficacy of a recently approved second-generation triazole (isavuconazole)
    • Enhanced understanding of the characteristics of and indications for currently available antifungals
    • Because fluconazole interacts with warfarin, phenytoin, and cyclosporine when given in a daily dose of 200 mg or higher, serum concentrations of these agents should be monitored when they are used in conjunction with fluconazole.

Treatment of Diabetic Foot

    • Development of guidelines for diagnosis and treatment of diabetic foot to help codify worldwide data across various specialties involved with diabetic foot
    • Using a specialized sealed dressing and a vacuum pump, the wound vacuum is a therapeutic system that implements a constant or intermittent negative pressure environment to accelerate wound healing in acute and chronic wounds
    • After successful revascularization, secondary procedures on the foot may be performed for maximal foot salvage, with the aim of addressing both the acute problem and the underlying cause. The basic goals of such procedures are to (1) remove infected bone (if present), (2) restore functional stability, and (3) reduce the risk of subsequent ulceration

Treatment of Diabetic Foot

    • Development of guidelines for diagnosis and treatment of diabetic foot to help codify worldwide data across various specialties involved with diabetic foot
    • Using a specialized sealed dressing and a vacuum pump, the wound vacuum is a therapeutic system that implements a constant or intermittent negative pressure environment to accelerate wound healing in acute and chronic wounds
    • After successful revascularization, secondary procedures on the foot may be performed for maximal foot salvage, with the aim of addressing both the acute problem and the underlying cause. The basic goals of such procedures are to (1) remove infected bone (if present), (2) restore functional stability, and (3) reduce the risk of subsequent ulceration

Candidiasis

    • Updated treatment options for patients with candidiasis
    • Evidence for efficacy of rapid Candida species identification products
    • Enhanced understanding of antifungal prophylaxis

Candidiasis

    • Updated treatment options for patients with candidiasis
    • Evidence for efficacy of rapid Candida species identification products
    • Enhanced understanding of antifungal prophylaxis

Feeding and Eating Disorders

    • With the DSM-5, rumination and pica are now placed in the same chapter as bulimia nervosa and anorexia nervosa.
    • In the DSM-5, diagnoses were modified and expanded to better describe patient diversity, especially with respect to age.
    • According to a recent study, implementation of the DSM-5 criteria may dramatically reduce residual eating disorder diagnoses within clinical settings.

Critical Care: Diagnostic Imaging Techniques 

    • Recently developed dual-energy chest radiographs can detect calcium in lesions or remove overlapping bone to confirm the presence of a lesion
    • Automatic tube current and tube potential modulation reduces computed tomography radiation risk by optimizing the radiation dose to the patient size and scan region
    • Positron emission tomography has limited applicability in low-grade adenocarcinoma and carcinoid tumors owing to poor fluorodeoxyglucose uptake in these clinical concerns

Pituitary, Thyroid, and Parathyroid Disorders and Considerations

    • Endocrine emergencies, such as thyroid storm and myxedema coma, still carry a high mortality rate and need to be promptly managed.
    • Syndrome of inappropriate antidiuretic hormone secretion remains the most common cause of hyponatremia, a common electrolyte abnormality encountered in the critically ill.
    • Nonthyroidal illness syndrome, or euthyroid sick syndrome, may occur as a response to acute illness or stress and should be differentiated from underlying thyroid disease.
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